December 2022 A7 Exam Dumps

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Exam Code: A7 Practice exam 2022 by Killexams.com team
An Introduction to Purchasing Strategy
CIPS Introduction study help
Killexams : CIPS Introduction study help - BingNews https://killexams.com/pass4sure/exam-detail/A7 Search results Killexams : CIPS Introduction study help - BingNews https://killexams.com/pass4sure/exam-detail/A7 https://killexams.com/exam_list/CIPS Killexams : New Injection Could Help Heal Spinal Cord Injuries: Study

A revolutionary jab that could repair spinal cord injuries has been developed by scientists. Paralyzed mice regrew nerves within 3 months following weekly injections, according to a new study.

The results of the study were published in the journal PLOS Biology.

Lead author Dr. Simone Di Giovanni, of Imperial College London, said: "This work shows a drug called TTK21 that is administered systemically once a week after a chronic spinal cord injury in animals can promote neuronal regrowth and an increase in synapses that are needed for neuronal transmission." He added that "this is important because chronic spinal cord injury is a condition without a cure where neuronal regrowth and repair fail."

Damage to the spinal cord interrupts the constant stream of electrical signals from the brain to the body. It can lead to paralysis below an injury. The medication triggers cells to regenerate. Long spindly parts of the severed nerves—called axons—were mended.

Damage to the spinal cord interrupts the constant stream of electrical signals from the brain to the body. It can lead to paralysis below an injury. Unsplash

Currently, spinal cord injury does not have any effective treatments. Physical rehabilitation can help patients regain some mobility. But for severe cases, the outcomes are extremely limited by the failure of spinal neurons to regenerate naturally.

The study showed TTK21 aided the regrowth of sensory and motor neurons when given to mice 12 weeks after severe injury.

In experiments, lab rodents with severe spinal cord injury lived in an enriched environment that gave them opportunities to be physically active—as is encouraged in human patients.

A nurse prepares syringes with the Pfizer coronavirus booster vaccination on January 20, 2022, in Tokyo, Japan. In experiments, lab rodents with severe spinal cord injury lived in an enriched environment that gave them opportunities to be physically active. Carl Court/Getty Images

Treatment lasted for 10 weeks. Several improvements were identified—the most noticeable being the sprouting of more axons in the spinal cord. Retraction of motor axons above the point of injury was also halted—and sensory axon growth increased.

These changes were likely due to the observed increase in gene expression related to regeneration, said Dr. Di Giovanni.

He added: "We are now exploring the combination of this drug with strategies that bridge the spinal cord gap such as biomaterials as possible avenues to Boost disability in SCI [spinal cord injury] patients."

For decades, this has remained a major challenge. Our body's central nervous system, which includes the brain and spinal cord, does not have any significant capacity to repair itself.

A model of a spine. Our body's central nervous system, which includes the brain and spinal cord, does not have any significant capacity to repair itself. Unsplash

In the U.K., an estimated 50,000 people are living with an SCI. Each year approximately 2,500 people are newly injured. It affects nearly 300,000 in the U.S. Life for these patients can be extraordinarily difficult.

Fewer than 3 percent ever recover basic physical functions. A third are re-hospitalized at least once a year.

Produced in association with SWNS Talker.

This story was provided to Newsweek by Zenger News.

Thu, 22 Sep 2022 06:54:00 -0500 en text/html https://www.newsweek.com/new-injection-could-help-heal-spinal-cord-injuries-study-1745280
Killexams : Tips and Tools to Help Students Study, Take Notes, and Focus

With a new academic year rolling around, students of all ages will be looking for help and guidance with their work—and there are a wealth of options on mobile app stores and the web to help you succeed.

Here we've picked out some of the best apps and services across multiple categories, including time management, homework help, note-taking, and more. Put them together and you've got a comprehensive toolkit for making sure that this year is a good one.

No matter what your requirements, courses, or study habits are, there should be something here for you (or for the young student in your life). You might be surprised at just how much difference the right app can make.

Trello

Trello can adapt itself to whatever purpose you have in mind.

Courtesy of Trello

The main appeal of Trello is its versatility: You can adapt the simple card-based interface in whichever way you want—whether to keep track of individual homework assignments or to log multiple research strands in an essay—and the software will adapt accordingly.

You can assign categories and deadlines to cards, attach files to them, and drop in to-do lists. However you decide to use Trello, you're going to find it straightforward to get around the app with easy drag-and-drop operations and a ton of options and features.

Trello (freemium for web, Android, iOS)

Socratic

Get help from Socratic with just about any topic.

Courtesy of Socratic

Powered by Google's artificial intelligence engines, Socratic is here to answer any question on any topic, whether you need step-by-step math explanations, a quick overview of a historical event or work of literature, or details of a particular set of biological processes.

Sun, 09 Oct 2022 23:10:00 -0500 en-US text/html https://www.wired.com/story/tips-apps-help-students-study-notes-homework-help/
Killexams : How Fat Cells Help Kick Parasites Out of Mice: Study

Fat cells play a surprising role in combating parasites, according to a study published today (October 14) in Science Immunology, which finds that fatty tissue surrounding the intestinal tracts of mice helps eject gut-infesting worms and fight future infections.

Jorge Caamano, an immunologist at the University of Birmingham who was not involved in the work, says that “the study brings to focus the idea that when we’re looking at the immune response, we shouldn’t just focus on” immune cells.

Scientists already knew that mesenteric adipose tissue—the fat that lines the intestines—contributes to the immune response to pathogens and cancer. But its role in fighting parasites wasn’t well-defined until study coauthor and immunologist Edward Pearce and his colleagues at Johns Hopkins Medical Institute examined how fat cells and immune cells each respond to parasitic infection. 

Pearce’s group was studying how animals gain immunity to such infections in a mouse model when, during a routine autopsy, a veterinarian on the team noticed that the mesenteric adipose tissue of mice infected with parasitic helminths (Heligmosomoides polygyru) stiffened over the course of an infection. Helminths are microscopic worms that infect the gut (and only the gut), leeching nourishment from their host. In mice, they’re used to model human parasitic infections.

The researchers then sought to determine the cause of the tissue stiffness. As they were investigating how different cell types in the tissue responded to infection, they discovered a previously undescribed communication between two cell types that they later found to be important for long-term immunity to parasites: Th2 cells, a type of T cell known to fight parasites, and stromal cells, which are stem cell-like cells found in fat tissue that can differentiate into cells that provide structural support for tissues.

The researchers first isolated the stiffened fat tissue from parasite-infected mice and normal fat tissue from their healthy counterparts. They then separated the tissue into its component cells. And to study how infection restructures the immune cells and structural cells in the tissue, the team employed a combination of single-cell RNA sequencing, flow cytometry, cell culture, and histology.

Their first observation was that in addition to their presence in the gut, Th2 cells infiltrated the animals’ adipose tissue during infection—which the researchers found surprising, says Pearce, “because this infection actually never gets into the adipose tissue. It stays in the gut.”

Then, the team found that these fat-infiltrating immune cells differ from typical Th2 cells, as they were releasing the powerful cytokine TGFβ as well as Amphiregulin, a molecule that stimulates wound healing. They were also activated differently. Instead of being activated by a T cell receptor, a protein complex that typically triggers T cell activity during infection, the Th2 cells identified in the study were activated by cytokines. “They behaved in a way like cells that are part of the innate immune system rather than the adaptive,” says Pearce. 

The researchers then cultured the stromal cells and discovered they became highly metabolically active in response to Amphiregulin and TGFβ produced by Th2 cells. The stromal cells also started to produce cytokines, which further activated Th2 cells as they fought the helminth infection. The researchers also blocked the Amphiregulin receptor EGRF in stromal cells and observed that the severity of infection increased, highlighting the importance of stromal cell activation in fighting infection. 

When the researchers took a closer look at the animals’ tissues, they realized Th2 cells and stromal cells were meeting up in special spaces in the tissue called interstitial spaces, which become enlarged during infection. There, Th2 cells triggered stromal cells to secrete collagen and extracellular matrix, resulting in the observed tissue-stiffening. 

The team also found that some of these changes are long-lasting. Though their tissues returned to normal stiffness shortly after infection, the mice still had elevated levels of Th2 cells for up to a year after their initial infection was cleared with a drug (the mice were infected with the parasite for 11 to 14 days). Th2 cells and stromal cells also mobilized more quickly in response to subsequent infections.

Though Pearce and his team are not quite sure why Th2 cells are invading adipose tissue in the first place, they intend to find out. 

The findings from the study could help scientists fight disease—and not just parasitic infections, says Pearce. The rapid softening seen after a parasitic infection stands in contrast to other diseases where tissue becomes stiffer over time, like fibrosis. “There are strong resolving mechanisms at work here. And if we can understand more about those, perhaps they can be used to treat the type of fibrosis that goes too far.”

Fri, 14 Oct 2022 09:06:00 -0500 en text/html https://www.the-scientist.com/news-opinion/how-fat-cells-help-kick-parasites-out-of-mice-study-70627
Killexams : MSc Operations, Project and Supply Chain Management / Course details

Course description

Put your organisational skills to the test and learn to help businesses manage the production and delivery of products and services in an increasingly globalised marketplace. Operations management is all about how to organise the production and delivery of products and services.

  • Gain the knowledge and skills to ensure that processes run smoothly, particularly in the face of opportunities and challenges arising from the increasingly global reach of business 
  • Cover the service, manufacturing, public and private sectors, showing how operations management, project management and supply chain management work
  • Opportunity to concentrate on particular aspects of operations management, supply chain management, project management and process improvement
  • Prepare for a career as a professional operations, project or supply chain manager
  • Strong foundation for progression to a PhD or an academic career within the field
  • Opportunity to concentrate on particular aspects of operations management, supply chain management, project management and process improvement, helping towards membership of the Chartered Institute of Purchasing and Supply .

Aims

During the course you will be taking 180 credits in all. The eight taught modules during semester one and two total 120 credits and consists of both compulsory and optional taught units which can be viewed in the list below.

By agreement with the Course Director, one elective unit may be taken from another Masters course - note that all elective units are subject to availability, timetabling constraints and what you have studied previously.

Over the summer period, you will carry out your Research Dissertation, worth 60 credits.  Certain units must be chosen in order to become a member of CIPS, and the dissertation must be on a procurement and supply-related theme. 

Examples of recent dissertation project courses include:

  • The future green supply chain in the retail industry: a shared value strategic perspective
  • Evaluation of cost performance in inventory management in reverse logistics
  • Using e-procurement to Boost supply chain management practices

Special features

CIPS accreditation

The course is accredited by the Chartered Institute of Purchasing and Supply (CIPS).

On completion of the MSc Operations, Project and Supply Chain Management course, students with three years' work experience in a relevant field of supply chain management can apply to become full members of CIPS.

  • As the course is accredited to CIPS, students with the required work experience will not need to take any further examinations to become full members of CIPS (as long as they have completed the required modules and the dissertation should focus on a procurement and supply related theme as part of the MSc).
  • Students without the required work experience (for example, recent graduates) can take the required modules and dissertation element of the MSc programme and on completion of three years relevant work experience can apply for full membership of CIPS. 
  • We are unable to answer individual enquiries about CIPS membership and you should apply directly to CIPS. Details of membership options can be obtained from the CIPS website .

Coursework and assessment

Assessment across the course units varies, and includes a combination of examinations, course work and group project assessment and presentations, in-class tests and assignments. A dissertation is also undertaken and normally ranges between 12,000 and 25,000 words.

Course unit list

The course unit details given below are subject to change, and are the latest example of the curriculum available on this course of study.

Disability support

Practical support and advice for current students and applicants is available from the Disability Advisory and Support Service. Email: dass@manchester.ac.uk
Sat, 10 Sep 2022 13:31:00 -0500 en text/html https://www.manchester.ac.uk/study/masters/courses/list/07783/msc-operations-project-and-supply-chain-management/course-details/
Killexams : Why this Stanford researcher says you should ask your friends for more favors: 'We are a collaborative society'

Need a ride to the airport? Or help hanging your curtain rod? These pesky tasks are often made easier by asking a friend for help, but many of us are reluctant to do so.

People consistently underestimate others' willingness to lend them a hand, according to a new study published in the journal Psychological Science.

Help-seekers also overestimate how inconvenienced the person they are asking for a favor will feel.

"It can be nerve-wracking to ask a stranger for help," says Xuan Zhao, a social science research scholar at Stanford University who co-authored the study with Nicholas Epley, a social cognition professor at the University of Chicago.

"In our research we found people underestimate both strangers' and friends' [desire to help]."

'We are a pro-social and collaborative society'

Throughout history, there has been a debate about whether we live in a selfish society or a collaborative society, Zhao says.

 "Over the past few recent decades, there has been more and more evidence that we are a pro-social and collaborative society," she says. "That's part of our winning strategy of evolution."

If you think about how you feel when you've helped out a friend, it might start to make sense.  

"Helping other people makes you feel good because it creates a moment of social connection," she says. "It makes you feel valued and needed by other people and if you are successful at helping them it makes you feel competent, and everyone likes feeling competent."

Helping other people makes you feel good because it creates a moment of social connection.

Xuan Zhao

Stanford Researcher

'People are taught to be self-sufficient'

Mon, 19 Sep 2022 02:30:00 -0500 en text/html https://www.cnbc.com/2022/09/17/new-study-you-should-ask-your-friends-for-help-more-heres-why.html
Killexams : CIPS inducts four new CIPS Fellows: Dr. Ken Barker, Derek Burt, Beverley Gooding, and Utpal Mangla

CIPS, Canada’s Association of Information Technology Professionals, has inducted four new CIPS Fellows: Dr. Ken Barker, Derek Burt, Beverley Gooding, and Utpal Mangla. Since 2005 CIPS Fellow Membership has been awarded to professionals in the Information Technology sector who have made an outstanding contribution to the advancement of the IT profession or industry in Canada.

Being awarded the CIPS Fellow status is earned recognition of significant development or outstanding contribution to the advancement of the profession, computer technology, the ICT sector or the adoption of ICT. Contributions can be made at a local, provincial, national or international level. Contributions can be made within or for the profession, business or government or industry. They can be made through research, systems development, education, authorship, public policy or advocacy.

The Fellow is the highest class of membership offered by CIPS and can only be obtained with approval from the CIPS National Board of Directors. Fellow Members have agreed to uphold the highest standards of ethics and professional conduct. They also help to promote CIPS and the association’s initiatives and causes within their sphere of influence. Fellow Members use the designation “FCIPS” after their name.

CIPS is pleased to induct the following four new CIPS Fellows and thanks them for their contribution to CIPS and Canada’s IT profession and community.

Dr. Ken Barker FCIPS, I.S.P., ITCP is a professor of computer science at the University of Calgary. He holds a PhD in computing science from the University of Alberta (1990) and has many years of experience working with industrial computer systems. He has interest in system integration, distributed systems, database systems, and the privacy and security of data repositories.

He has served as the dean of the faculty of science and as head of computer science at the University of Calgary. He is the director of the University of Calgary’s Institute for Security, Privacy and Information Assurance and the president of the Alberta body of the Canadian Information Processing Society (CIPS Alberta). He is a Fellow of the Canadian Global Affairs Institute, a Senior Member of the IEEE, and a Life-time Member of the ACM.

Ken is currently the President of CIPS Alberta and is a past president of the Canadian Association of Computer Science (CACS/AIC) in addition to having served on the Computer Science Accreditation Council.  As the director of research laboratories at the University of Calgary and University of Manitoba he has supervised over 70 graduate students, in addition to several post-doctorates and research assistants. Dr. Barker has published over 250 peer-reviewed publications.

Lean more at Ken’s CIPS Fellows profile at: https://cips.ca/kenbarker/

Derek Burt, FCIPS, I.S.P., ITCP has been a CIPS member for over a decade and was a long-time volunteer with CIPS in Saskatchewan (including serving as the President of CIPS Regina and a member of the CIPS Saskatchewan Governance Transition Taskforce) before relocating to Alberta in 2013. Derek is currently serving as Acting Treasurer for CIPS Alberta and has been Chair of the CIPS National Board of Directors since 2017.

In 2010, Derek was awarded the Marilyn Harris Award for IT Professionalism. Derek graduated from a CIPS-accredited computer science program at the University of Regina and has served on numerous private and public boards.

Derek is currently an Enterprise Architect and member the IT Architecture team at WestJet Airlines, Ltd. He is an IT Architect by trade, whose primary expertise lies in Enterprise Architecture as well as Business, Solution, and Application Architecture, particularly producing IT architectures for open platforms. He has experience leading projects, teams, and organizations, has worked with a wide variety of clients from across North America, and has been a frequent public speaker.

Lean more at Derek’s CIPS Fellows profile at: https://cips.ca/derekburt/

Beverley Gooding, FCIPS, I.S.P. (ret.)  has worked in the IT sector since 1970, working at SaskTel, INCO, and SGI,.and retired in 2014. Bev has been a CIPS member and I.S.P. Certification holder since 1991 and has held many positions in CIPS over the years on both CIPS Saskatchewan and CIPS National, including being on the CIPS National Board of Directors from 2001 – 2008 as a Regional Director and National Student Director.

In CIPS Regina (a former section of CIPS Saskatchewan) she was co-Chair of the Programming Committee, Regional Director, Vice-President, President, and Chair of the annual conference, Spring Seminar.

Bev became the CIPS Saskatchewan Registrar in 2005 and still holds this position on the CIPS Saskatchewan Executive Board.

Bev noted: “Personally, I am very grateful for the opportunities I have been provided while working with CIPS. I have developed and enhanced various skills which have helped me personally and with my career. e.g. project management, working with volunteer staff, interviewing, mentoring, learning nuances of dealing with government, etc.”

Lean more at Bev’s CIPS Fellows profile at: https://cips.ca/beverleygooding/

Utpal Mangla (MBA, PEng, CMC, FCIPS, I.S.P., ITCP, PMP, ITIL, CSM, FBCS) is a General Manager responsible for Telco Industry & EDGE Clouds in IBM. Prior to that, he was the VP, Senior Partner and Global Leader of TME Industry’s Centre of Competency. In addition, Utpal led the ‘Innovation Practice’ focusing on AI, 5G EDGE, Hybrid Cloud and Blockchain technologies for clients worldwide.

Utpal has been with IBM (and PwC) since 1998. With 20+ years of experience, Utpal is a highly motivated & dynamic leader who thrives in challenging environments. He is reputed for his trust, problem solving and organizational skills. Recipient of numerous client excellence awards, he is recognized as “IBM Top Talent”.

Utpal is a regular speaker at industry forums, univ and business conferences globally, including MWC, THINK, TMForum, Dreamforce, Cannes, Fierce 5G and CEM Telecoms. With 50+ articles, Utpal contributes to industry blogs, analyst reports and emerging marketplace trends. He has been quoted in Fortune, Bloomberg, GSMA, LF and BusinessWire.

Utpal is an active contributor & member of FORBES council, AI Think Tank at Cognitive World, is current chair of ISSIP Strategy Council, member of CompTIA’s IoT Advisory leadership and was on board of ATIS. Utpal is also member of IBM’s Executive Partner Promotion committee, Talent Ecosystem & 5G EDGE Acceleration teams.

Lean more at Utpal Mangla’s CIPS Fellows profile at: https://cips.ca/utpalmangla/

Learn more about CIPS Fellows at https://cips.ca/fellows/ and view CIPS Fellow Members at: https://cips.ca/fellowmembers/

ABOUT CIPS:

CIPS (Canadian Information Processing Society) is a National IT Federation of 10 Provincial regulators that license IT professionals in Canada and abroad. Since 1958 CIPS has helped advance Canada’s IT profession by establishing standards, best practices, and integrity for the benefit of IT professionals and the public interest. As “Canada’s Association of Information Technology Professionals” we represent thousands of members across the country.

CIPS provides:

Learn more about CIPS at www.cips.ca

Follow CIPS on LinkedIn: https://www.linkedin.com/company/canadian-information-processing-society/

FOR MORE INFORMATION CONTACT:

Jonathan Elias
Chief Marketing Officer
CIPS – Canada’s Association of IT Professionals
jelias@cips.ca

Mon, 19 Sep 2022 07:32:00 -0500 en-US text/html https://www.itbusiness.ca/press-release/cips-inducts-four-new-cips-fellows-dr-ken-barker-derek-burt-beverley-gooding-and-utpal-mangla
Killexams : Breath training may help reduce blood pressure by serving as a 'dumbbell for the diaphragm': New study

Strength training isn’t just for biceps.

It may also provide support for the muscles that help us breathe to reduce blood pressure.

A daily dose for six weeks of high-resistance inspiratory muscle strength training (IMST) reduced the systolic blood pressure by an average of nine millimeters of mercury, according to a new study published in the Journal of Applied Physiology.

HYPERTENSION, THE SILENT KILLER — WHAT IT IS?

"In our research, we’ve found that high-resistance inspiratory muscle strength training, consisting of 30 resisted inhalations per day through a handheld device, lowered systolic blood pressure by 9 mmHg on average," said lead author Dr. Daniel Harrison Craighead.

He is assistant research professor of integrative physiology at the University of Colorado Boulder.

Researchers wanted to apply the same concept of strength training used for keeping muscles healthy to the muscles that help us inhale — such as our diaphragm. (iStock)

"This is important," Craighead said, "because a reduction in blood pressure of that level would reduce someone’s risk for getting cardiovascular disease and other health problems associated with high blood pressure." 

Since muscles weaken over time, strength training is often used to keep the muscles of the body healthy.

HOW TO REVERSE YOUR BIOLOGICAL AGE AND FEEL YOUNGER WITHOUT SPENDING A FORTUNE 

Craighead, however, wanted to apply that same concept to the muscles that help us inhale, such as the diaphragm.

Along with other researchers, he recruited healthy volunteers ages 18-82 to use a device called PowerBreathe, which provides resistance training for the muscles that help us inhale. (There are several such devices on the market.)

The study's participants were asked to use the device for five minutes a day for six weeks.

"Just as you would use a heavier dumbbell as your bicep strength improves, you can increase the resistance on the breathing device as your breathing strength improves." (iStock)

It’s often referred to as the "dumbbell for your diaphragm" because it creates resistance when we take a breath, according to the PowerBreathe website. 

"Just as you would use a heavier dumbbell as your bicep strength improves, you can increase the resistance on the breathing device as your breathing strength improves," the website added.

The new study found that performing 30 breaths per day for six weeks lowered systolic blood pressure by approximately 9 millimeters of mercury, which is similar to the reduction attained by conventional aerobic exercise such as walking, running or cycling.

The lead author of a new study said the breathing "protocol takes only 5-10 minutes per day, so we hope it’ll be easy for people to adhere to."

"In addition, the protocol takes only 5-10 minutes per day, so we hope it’ll be easy for people to adhere to," Craighead told Fox News Digital. 

"It can easily be done while doing things like watching TV or waiting for your coffee to brew."

Lowering systolic blood pressure by 10 mm Hg reduces the risk of stroke by about 35% and that of heart disease events by approximately 25% at age 65, according to a British Medical Journal report. 

What is high blood pressure?

The American Heart Association defines a normal blood pressure as less than 120/80 mm Hg.

The top number is the systolic blood pressure, which is pressure inside the artery when the heart is contracting and sends blood throughout the body.

A nurse measures a patient's blood pressure. "A patient is at risk for high blood pressure, also known as hypertension, if the systolic blood pressure readings are consistently 120-129, which is termed elevated blood pressure," said one health professional. (iStock)

The bottom number is the diastolic blood pressure, or when pressure of the artery when the heart is at rest and fills with blood, according to Johns Hopkins Medicine.

A patient is at risk for high blood pressure, also known as hypertension, if the systolic blood pressure readings are consistently 120-129, which is termed elevated blood pressure.

People who are diagnosed with stage 1 hypertension have systolic blood pressure readings that consistently range from 130-139 mm Hg or diastolic studying that range from 80-89 mm Hg.

"High blood pressure is a common problem and contributes to stroke, heart failure, kidney failure and a variety of other cardiovascular complications."

When people are diagnosed at this stage, lifestyle changes are often recommended first before starting any medication.

"High blood pressure is a common problem and contributes to stroke, heart failure, kidney failure and a variety of other cardiovascular complications," Dr. Deepak L. Bhatt, professor of medicine at Harvard Medical school, told Fox News Digital. 

"Lifestyle measures, such as restricting salt intake and weight loss, can help lower blood pressure, though many people with high blood pressure eventually end up needing medications," added Bhatt. 

"Many people with high blood pressure eventually end up needing medications," said a professor medicine at Harvard Medical School.  (iStock, File)

He is also executive director of interventional cardiovascular programs at Brigham and Women’s Hospital Heart & Vascular Center in Boston.

Stage 2 hypertension is when systolic blood pressure readings consistently range at 140/90 mm Hg or higher, according to the American Heart Association.

"Potentially, breath training, as was done in this [new] study, might help strengthen the muscles involved with breathing and additionally lower blood pressure," Bhatt said.

"It seems like a safe approach," he added, "though further study is needed to determine just how effective it may be and who the ideal candidates might be." 

People who are on high blood pressure medications, said Bhatt, should not stop these medications without consulting their physicians first.

"We need to do much longer studies to confirm that we actually see a lower rate of blood pressure-associated conditions in people who do this training," said the lead author of a new study. 

"I don’t think it will be a magic fix on its own," Craighead of the University of Colorado Boulder told Fox News Digital about IMST, the strength training process for respiratory breathing muscles.

"A reduction in systolic blood pressure won’t be enough to fully control blood pressure in people with more than mild hypertension," he said.

"However, so far we’ve seen that it is effective in people already taking antihypertensive medications — so it could be a good ‘add-on’ therapy to medications."

He also noted it has additional benefits to conventional exercise "because the breathing training is so different from running or walking — but that question still needs to be confirmed with further research."

How does breath training work?

Endothelial cells cover the lining of the blood vessels, which in turn help produce a key compound that protects the heart called nitric oxide, according to Cleveland Clinic.

Nitric oxide widens the blood vessels, which promotes healthy blood flow.

The study found that six weeks of inspiratory-muscle strength training increased endothelial function by about 45%.

Limitations of the study

Craighead noted that his current study has some limitations, including that it only tested participants for six weeks.

"We need to do much longer studies to confirm that we actually see a lower rate of blood pressure-associated conditions in people who do this training," he told Fox News Digital.

SHOULD YOU GET THE FLU SHOT THIS YEAR? DOCTORS REVEAL THEIR DECISION

He also noted that most participants in his study were non-Hispanic white adults, so it’s difficult to generalize the research to a diverse population of people.

"We need to learn about how effective this breathing training is when people train on their own, without researcher oversight."

All the research was done in a controlled laboratory setting, said Craighead, so "we need to learn about how effective this breathing training is when people train on their own, without researcher oversight."

Future research needed

He hopes, however, that the study results inspire more research on high-resistance inspiratory muscle strength training. 

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"If the health benefits are confirmed in larger trials with longer treatment durations, then I can see this becoming another important tool in the toolbox for helping control blood pressure," Craighead added.

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"I think it is really promising because it is so time-efficient — and thus far has been shown to be safe in the groups investigated."

Fri, 23 Sep 2022 23:01:00 -0500 Fox News en text/html https://www.foxnews.com/health/breath-training-may-help-reduce-blood-pressure-serving-dumbbell-diaphragm-new-study
Killexams : Study: Eating a bigger breakfast may help control appetite

Sep 16, 2022, 12:02pmUpdated on Sep 16, 2022

By: News 12 Staff

A new study from the The University of Aberdeen shows bigger breakfasts might be better for controlling appetite.

Scientists controlled people's meals to see the effects of large breakfasts and dinners.

They found people seemed to burn the same calories whenever they had their biggest meal of the day.

However, people's appetites were noticeably smaller after a big breakfast.

Fri, 16 Sep 2022 00:03:00 -0500 text/html https://longisland.news12.com/study-eating-a-bigger-breakfast-may-help-control-appetite
Killexams : Folic acid may help lower risk of suicide attempts, study says. Experts say it could be a ‘major breakthrough.’

Prescription folic acid may help lower the risk of suicide attempts. (Photo: Getty Images)

Taking prescription folic acid is associated with a significantly lower risk of suicide attempts, according to a recent study published in JAMA Psychiatry. Experts say this could potentially offer a “major breakthrough” in suicide prevention.

The large-scale study, which looked at the data of 867,000 American adults over two years, showed a beneficial association between taking prescription folic acid — a B vitamin that helps the body make healthy new cells — and a 44% lower rate of suicide attempts and intentional self-harm. The research also found that every additional month of folic acid treatment was associated with a 5% reduction in suicidal event rates.

That’s significant, given that suicide is a leading cause of death in the U.S., according to the Centers for Disease Control and Prevention (CDC). In 2020, an estimated 12.2 million American adults seriously contemplated suicide, 3.2 million planned a suicide attempt and 1.2 million attempted suicide.

What do experts think about the study?

Dr. Tatiana Falcone, a psychiatrist with Cleveland Clinic who was not involved in the study, tells Yahoo Life that the results are “really interesting.” She points out that the researchers ruled out possible factors that could “potentially confound the results” and still found that prescription folic acid made a difference. The researchers also compared two groups — one taking prescription folic acid and another taking cyanocobalamin (vitamin B12) as a control group — and found that the folic acid group experienced fewer suicide attempts.

Sanam Hafeez, a neuropsychologist and director of Comprehend the Mind, who was not involved in the study, tells Yahoo Life that results are “impressive.” However, she agrees with Falcone that more research is needed. Hafeez also says it’s important to point out that the folic acid used for the purpose of this study was in a prescription form — “not the OTC supplemental kind,” she says.

But if further studies confirm folic acid — which is inexpensive and widely available — as a suicide prevention tool, “it will be significant for the patients that have low folate levels associated with depression or suicidal thoughts,” says Falcone.

Hafeez agrees, saying: “It would not only be a major breakthrough in the treatment of depression but also medication-resistant depression.”

So how does folic acid help?

Some studies suggest there’s a link between low levels of folate — the natural form of the B vitamin — and depression. That may be because folate plays a role in forming serotonin, a neurotransmitter that helps regulate mood. Medications such as selective serotonin reuptake inhibitors (SSRIs) help treat depression and other mood disorders by increasing levels of serotonin in the brain.

But, says Falcone, “Some percentage of patients with depression have abnormalities in the folate acid metabolism," which will impact their response to SSRI antidepressants.

"Treatment with folinic acid has been reported beneficial in patients with treatment-resistant depression who have decreased levels of folate … in their cerebrospinal fluid,” she adds.

Falcone adds that not waiting to get treatment for depression is crucial. “The longer that the depressive symptoms persist, the longer that the suicidal thoughts persist, the more likely that the patient will continue to worsen,” she says, explaining that this is why it’s “important to work collaboratively with your doctor to find the appropriate combination of treatments that is right for the patient.” She adds: “A combination of medication and therapy is the best.”

If you or someone you know is experiencing suicidal thoughts, call 911 or the National Suicide Prevention Lifeline at 988 or 1-800-273-8255, or text HOME to the Crisis Text Line at 741741.

Wellness, parenting, body image and more: Get to know the who behind the hoo with Yahoo Life's newsletter. Sign up here.

Wed, 12 Oct 2022 10:58:00 -0500 en-US text/html https://www.yahoo.com/lifestyle/folic-acid-lower-risk-suicide-attempts-study-222707354.html
Killexams : Snacking on Walnuts May Help Add Years to Your Life: Study

Snacking on walnuts instead of biscuits or sweets may add years to your life, according to research. A handful of nuts a day reduces the risk of heart attacks, strokes, and other life-threatening conditions linked to obesity.

The superfood is packed with chemicals that protect DNA by destroying reactive molecules, or oxidants. The study was published in the Nutrition, Metabolism, & Cardiovascular Diseases journal.

A study found regular consumers were slimmer and fitter as they got older. They had fewer harmful fats, called triglycerides, and lower blood pressure.

A picture showing walnuts. Snacking on walnuts instead of biscuits or sweets may add years to your life, according to new research. Unsplash

"Walnut eaters seem to have a unique body phenotype that carries with it other positive impacts on health like better diet quality," said lead author Professor Lyn Steffen of the University of Minnesota.

"This is especially so when they start eating walnuts from young into middle adulthood—as the risk of chronic diseases like heart disease, obesity, and diabetes elevates," Steffen said.

The findings are based on more than 3,000 individuals across the U.S. who were tracked for three decades, into their fifties.

Among walnut eaters, average weight gain was less, there were fewer cases of obesity, and fasting blood glucose was lower. They also had lower bad cholesterol than eaters of other nuts.

A model of a human heart. Among walnut eaters, average weight gain was less, there were fewer cases of obesity, and fasting blood glucose was lower. Unsplash

Nut consumers showed an advantage in relation to diet quality, but walnut consumers appear to have a better heart disease risk factor profile than other groups, even after accounting for overall diet quality.

"The surprising, healthy shifts in the overall dietary pattern of walnut consumers suggests walnuts may act as a bridge or 'carrier' food," Steffen said.

Walnuts are rich in healthy plant chemicals including polyunsaturated fat and omega fatty acids which combat bad cholesterol. They dampen inflammation that can lead to a clotted vessel—and trigger a heart attack or stroke.

A picture showing walnuts. Walnuts are rich in healthy plant chemicals including polyunsaturated fat and omega fatty acids which combat bad cholesterol. Unsplash

The study says walnuts might be an easy and accessible food choice to boost the heart when eaten up to middle age. It could be due to the "unique combination of nutrients" and their effect on health, Steffen said.

About an ounce a day—equivalent to seven whole walnuts—has four grams of protein and two grams of fiber. It is also a good source of magnesium which is important for the muscles and nerves and increases energy.

The study—backed by the National Heart, Lung, and Blood Institute in the U.S.—was also partly funded by the California Walnut Commission.

It took into account other heart disease risk factors including overall diet, smoking, and body composition.

Produced in association with SWNS Talker.

This story was provided to Newsweek by Zenger News.

Tue, 20 Sep 2022 09:14:00 -0500 en text/html https://www.newsweek.com/snacking-walnuts-help-years-your-life-study-1744388

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